Ganoderic acid D, E, F, and H and lucidenic acid D, E, and F, new triterpenoids from Ganoderma lucidum.

Sensitometric characteristics of D-, E- and F-speed dental radiographic films in manual and automatic processing

BACKGROUND: The purpose of this study was to evaluate the sensitometric characteristics of Ultraspeed, Ektaspeed Plus and Insight dental radiographic films using manual and automatic processing systems. METHODS: In this experimental invitro study, an aluminum step-wedge was used to construct characteristic curves for D-, E- and F-speed radiographic films (Kodak Eastman, Rochester, USA). All fil...

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Unified total synthesis of the natural products endiandric acid A, kingianic acid E, and kingianins A, D, and F.

A measure of the strength of a synthetic strategy is its versatility: specifically, whether it allows structurally distinct targets to be prepared. Herein we disclose a unified approach for the total synthesis of natural products of three distinct structural types, all of which occur naturally as racemic mixtures. The point of divergence involves the terminal alkylation of a conjugated tetrayne...

Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae.

The antiinflammatory properties of triterpenoids and steroids from both Ganoderma lucidum and Ganoderma tsugae were studied. Twelve compounds, including ergosta-7,22-dien-3beta-ol (1), ergosta-7,22-dien-3beta-yl palmitate (2), ergosta-7,22-dien-3-one (3), ergosta-7,22-dien-2beta,3alpha,9alpha-triol (4), 5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol (5), ganoderal A (6), ganoderal B (7), gano...

Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells.

Ganoderma lucidum is a well-known traditional Chinese medicinal herb containing many bioactive compounds. Ganoderic acid T (GA-T), which is a lanostane triterpenoid purified from methanol extract of G. lucidum mycelia, was found to exert cytotoxicity on various human carcinoma cell lines in a dose-dependent manner, while it was less toxic to normal human cell lines. Animal experiments in vivo a...